Difference between plasma and serum

If you have been left homework: describe the difference between plasma and serum, then you have come to the right place because we are going to effectively explain the difference between plasma and serum.

What are the differences between plasma and serum?

Plasma and serum are a fundamental part of the blood. That is, blood is made up of serum, plasma, white blood cells, and red blood cells. The main difference between serum and plasma is the coagulation factors.

From coagulation we can say that it requires a substance called fibrinogen for it to be achieved. When plasma is separated from blood with serum, the plasma retains fibrinogen for coagulation, whereas serum is the part of the blood that remains after this fibrinogen is removed.

What remains of the blood after the red blood cells, white blood cells, and clotting factors have been removed?

To understand it we have to state that blood serum is water that dissolves with hormones, minerals, proteins and carbon dioxide. This is a very important source of electrolytes, so it could be said that its function as blood serum is essential for the balance of internal systems.

Plasma is a clear, yellow liquid and is part of the blood . It can also be found in intramuscular fluids and lymphs. This is the part of the blood that contains within itself fibrin and other factors that help coagulation. It is so important that it occupies 55% of the total blood volume . The main component of blood plasma is water.

How are blood components divided?

It is a complex process, in short, the blood plasma is prepared to spin inside a test tube containing blood. The machine that spins it is called a centrifuge and it stops until the globules are separated at the end of the tube.

Once this is done, the plasma separates. The normal level of plasma in blood has a density of 1,025 kg/l. As a curious fact, the plasma that results from this process can be stored up to 10 without being damaged . It can be said at this point that plasma is the cell-free part of the blood and is usually manipulated with anticoagulants.

Serum is then the liquid part of the blood after coagulation . It carries between 6 and 8% of the proteins (albumin and globulins) that make up the blood. When blood is withdrawn and stops clotting, that same clot shrinks over time. Serum is squeezed out when this clot is reduced. The proteins found within the whey are separated through a process called electrophoresis.

In summary

  • Plasma is part of the blood that contains: serum and coagulation factors.
  • Serum is the part of the blood that remains after clotting factors such as fibrin have been removed.
  • Plasma contains water and coagulation factors, while serum contains proteins such as globulins and albumins.
  • The blood serum is made up of water and is yellowish in color since it dissolves between mineral proteins, hormones, carbon dioxide, this is also an important source of electrolytes.

Frequently asked questions that summarize what was explained

How is serum extracted from blood?

To separate the serum from the blood, it must be centrifuged at 1600 g for 10 minutes at room temperature. These factors reduce contamination with platelets. You must grab the serum that is at the top of the centrifuged tube and avoid grabbing the gel or clot.

What is the difference between blood and plasma?

In summary, the plasma contains serum and coagulation factors, when the coagulants such as fibrin have been eliminated, this liquid becomes serum.

What is blood serum?

Hematic serum or blood serum is the result of allowing it to coagulate and eliminate the clot. It is an equivalent to blood plasma, but without involving the proteins that are seen in coagulation (fibrinogen).

How is plasma obtained from blood?

It is the result of having separated the homostatic factors by blood coagulation. Plasma is usually gritty, salty, and translucent yellowish in color.

What is the whey?

Serum is a term that has different applications. In medicine, serum is a liquid that is composed of various organisms.

What are the proteins found in the blood?

  • globulins
  • fibrinogen
  • Albumins
  • Lipoproteins.

What components does the serum have?

It contains electrolytes, water and other substances such as carbon and some expander polysaccharides.

What is blood plasma and what is it used for?

As mentioned, plasma is a platelet-rich substance so it is very useful in the medical field. In the orthopedic area it is used for plastic and dental surgery, it is also used in the field of dermatology, its efficiency is due to its capacity for wound healing and skin rejuvenation.

What is the composition of the blood?

Blood in the human adult body is distributed as follows: 4.5 and 6 liters of blood. 55% is plasma and 45% red blood cells, white blood cells and platelets.

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