Medicine

Difference Between Losartan and Diovan

Main difference

The main difference between Losartan and Diovan is that Losartan is the generic name of the drug and Diovan is the brand name of a drug.

Losartan vs. Diovan

Losartan is a generic term, on the other hand, Diovan is the brand name. Losartan is available as losartan potassium, while Diovan is available as valsartan potassium. Losartan is a short-acting drug, on the other hand, Diovan is a relatively long-acting drug. Losartan at lower doses should be taken twice a day, while Diovan is taken once a day. Losartan does not cause chest pain or low blood sugar. On the other hand, Diovan causes chest pain and low blood sugar. Losartan does not cause insomnia or muscle cramps, on the other hand, Diovan causes insomnia and muscle cramps. Losartan reduces the risk of stroke in hypertensive patients and patients with left ventricular hypertrophy, while Diovan does not reduce such risks.

Comparison chart

losartan Diovan
Losartan is the antihypertensive drug. Diován contains valsartan, which is an antihypertensive drug.
drug category
Angiotensin receptor blocker. Angiotensin receptor blocker.
Mechanism of action
block angiotensin II block angiotensin II
Sales Available
losartan potassium Valsartan potassium
Side effects that are different for each drug
Headache, abdominal pain, nausea. Chest pain, insomnia, low blood sugar, muscle cramps
Other therapeutic uses
Reduce the risk of stroke in hypertensive patients and left ventricular hypertrophy
Treat patients with type 11 diabetes
Heart failure
Reduce the risk of congestive heart failure

What is Losartan?

Losartan is the active therapeutic moiety of Cozaar, which is used to lower blood pressure in patients suffering from high blood pressure. Losartan is available as Losartan potassium, and is also available as Losartan potassium and hydrochlorothiazide combination tablets. Losartan is used alone or with other medications to lower blood pressure. Losartan treatment takes about six weeks for adequate blood pressure reduction. Losartan is also used to treat other medical conditions such as heart failure, left ventricular enlargement, and diabetic kidney disease. Losartan is the angiotensin receptor blocker and shows its therapeutic actions by blocking the binding of angiotensin II to angiotensin I receptors. Losartan delays diabetic nephropathy. Losartan slows the progression of kidney disease in patients with type 2 diabetes. Losartan also finds its role in the reduction of microalbuminuria or proteinuria. Losartan is recommended for patients under 55 years of age who cannot tolerate the ACE inhibitor. Losartan is considered best for the primary prevention of adverse cardiovascular events. When taken orally, losartan is well absorbed and after metabolism produces its metabolite which is the five carboxylic acid metabolite. The use of losartan should be discontinued as soon as the pregnancy test is positive, as it causes fetal toxicity causing fatal injury or death. The use of losartan can cause some side effects, which are dizziness, back pain, nasal congestion and upper respiratory tract infections. Diabetic patients experience some unique side effects like diarrhea, low blood pressure, fatigue, chest pains, low blood glucose, and high potassium. More serious side effects include low blood pressure and allergic reactions. Diabetic patients and patients using aliskiren should not use Losartan.

Example

Famous brands that contain Losartan are Hyperten, Losagen, etc.

What is Diovan?

Diovan contains valsartan which is used by patients with high blood pressure, diabetic kidney disease and heart failure. Diovan is considered best for the initial treatment of hypertension. Diovan causes blood vessels to relax and activates aldosterone by blocking the actions of angiotensin I, leading to a reduction in blood pressure. Diovan acts as an angiotensin type I receptor antagonist. Diovan is an orally active non-peptide drug. Diovan tablets contain valsartan in the strength of 40 mg, 80 mg, 160 mg, or 320 mg tablets. The inactive ingredients in Diovan are colloidal silicon dioxide, polyethylene glycol 8000, iron oxides (yellow, black, and red), magnesium stearate, crospovidone, hydroxypropylmethylcellulose microcrystalline cellulose, and titanium dioxide. Clinical studies of Diovan show various side effects, but the side effects are mild, and in some cases, patients need to stop therapy. Diovan shows side effects like diarrhea, dizziness, low blood pressure, and some less common side effects include fatigue, joint pain, and back pain. Diovan interacts with food. The use of Diovan during pregnancy can harm the baby and its use in nursing mothers is not recommended. Diován should not be used if the patient is allergic to the active ingredient or is dehydrated. Since Diovan causes some dizziness, do not use heavy machinery or drive after taking it. Diovan increases potassium levels, so consult a doctor before taking any potassium supplements while using Diovan. Diovan should not be taken with lithium and aliskiren, as both increase blood potassium. but side effects are mild, and in some cases, patients must discontinue therapy. Diovan shows side effects like diarrhea, dizziness, low blood pressure, and some less common side effects include fatigue, joint pain, and back pain. Diovan interacts with food. The use of Diovan during pregnancy can harm the baby and its use in nursing mothers is not recommended. Diován should not be used if the patient is allergic to the active ingredient or is dehydrated. Since Diovan causes some dizziness, do not use heavy machinery or drive after taking it. Diovan increases potassium levels, so consult a doctor before taking any potassium supplements while using Diovan. Diovan should not be taken with lithium and aliskiren, as both increase blood potassium. but side effects are mild, and in some cases, patients must discontinue therapy. Diovan shows side effects like diarrhea, dizziness, low blood pressure, and some less common side effects include fatigue, joint pain, and back pain. Diovan interacts with food. The use of Diovan during pregnancy can harm the baby and its use in nursing mothers is not recommended. Diován should not be used if the patient is allergic to the active ingredient or is dehydrated. Since Diovan causes some dizziness, do not use heavy machinery or drive after taking it. Diovan increases potassium levels, so consult a doctor before taking any potassium supplements while using Diovan. Diovan should not be taken with lithium and aliskiren, as both increase blood potassium. Diovan shows side effects like diarrhea, dizziness, low blood pressure, and some less common side effects include fatigue, joint pain, and back pain. Diovan interacts with food. The use of Diovan during pregnancy can harm the baby and its use in nursing mothers is not recommended. Diován should not be used if the patient is allergic to the active ingredient or is dehydrated. Since Diovan causes some dizziness, do not use heavy machinery or drive after taking it. Diovan increases potassium levels, so consult a doctor before taking any potassium supplements while using Diovan. Diovan should not be taken with lithium and aliskiren, as both increase blood potassium. Diovan shows side effects like diarrhea, dizziness, low blood pressure, and some less common side effects include fatigue, joint pain, and back pain. Diovan interacts with food. The use of Diovan during pregnancy can harm the baby and its use in nursing mothers is not recommended. Diován should not be used if the patient is allergic to the active ingredient or is dehydrated. Since Diovan causes some dizziness, do not use heavy machinery or drive after taking it. Diovan increases potassium levels, so consult a doctor before taking any potassium supplements while using Diovan. Diovan should not be taken with lithium and aliskiren, as both increase blood potassium. Diovan interacts with food. The use of Diovan during pregnancy can harm the baby and its use in nursing mothers is not recommended. Diován should not be used if the patient is allergic to the active ingredient or is dehydrated. Since Diovan causes some dizziness, do not use heavy machinery or drive after taking it. Diovan increases potassium levels, so consult a doctor before taking any potassium supplements while using Diovan. Diovan should not be taken with lithium and aliskiren, as both increase blood potassium. Diovan interacts with food. The use of Diovan during pregnancy can harm the baby and its use in nursing mothers is not recommended. Diován should not be used if the patient is allergic to the active ingredient or is dehydrated. Since Diovan causes some dizziness, do not use heavy machinery or drive after taking it. Diovan increases potassium levels, so consult a doctor before taking any potassium supplements while using Diovan. Diovan should not be taken with lithium and aliskiren, as both increase blood potassium. Diovan increases potassium levels, so consult a doctor before taking any potassium supplements while using Diovan. Diovan should not be taken with lithium and aliskiren, as both increase blood potassium. Diovan increases potassium levels, so consult a doctor before taking any potassium supplements while using Diovan. Diovan should not be taken with lithium and aliskiren, as both increase blood potassium. since both increase potassium in the blood. Diovan increases potassium levels, so consult a doctor before taking any potassium supplements while using Diovan. Diovan should not be taken with lithium and aliskiren, as both increase blood potassium. Diovan increases potassium levels, so consult a doctor before taking any potassium supplements while using Diovan. Diovan should not be taken with lithium and aliskiren, as both increase blood potassium. since both increase potassium in the blood. Diovan increases potassium levels, so consult a doctor before taking any potassium supplements while using Diovan. Diovan should not be taken with lithium and aliskiren, as both increase blood potassium. Diovan increases potassium levels, so consult a doctor before taking any potassium supplements while using Diovan. Diovan should not be taken with lithium and aliskiren, as both increase blood potassium. so consult a doctor before taking any potassium supplements while using Diovan. Diovan should not be taken with lithium and aliskiren, as both increase blood potassium. so consult a doctor before taking any potassium supplements while using Diovan. Diovan should not be taken with lithium and aliskiren, as both increase blood potassium.

Example

Diovan is a brand of valsartan and some other brand of valsartan is useless.

Key differences

  1. Losartan is a generic name of a drug while Diovan is a brand name of a drug.
  2. The name of losartan salt is losartan potassium, on the other hand, the name of Diován salt is valsartan potassium
  3. Losartan has a short duration of action, on the other hand, Diovan has a long duration of action.
  4. Low-dose losartan is given more than once a day, while Diovan is given once a day.
  5. Losartan use does not cause chest pain and low blood sugar as side effects, on the other hand, Diovan use causes chest pain and low blood sugar as side effects.
  6. The use of losartan reduces the risk of cerebrovascular accidents in hypertensive patients and patients with left ventricular hypertrophy, while Diovan does not reduce these risks in hypertensive patients and patients with left ventricular hypertrophy.
  7. Losartan is not used in heart failure whereas Diovan is used in heart failure.
  8. Losartan is not used in CHF while Diovan is used in CHF.

Final Thought

The conclusion of the above discussion is that both Losartan and Diovan are angiotensin receptor blockers and are used to treat hypertension and some other cardiovascular disorders.

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