Biology

Difference between hemostasis and thrombosis

Main difference

The main difference between hemostasis and thrombosis is that hemostasis is the natural clotting process, which stops excessive bleeding from an injury, while thrombosis is the process in which a blood clot forms within the blood vessel to block normal blood flow. blood through the circulatory system.

Hemostasis versus thrombosis

Haemostatics is considered as the natural clotting process within the body, which occurs primarily to stop the excessive flow of blood from a wall of a ruptured blood vessel that occurs due to injury. On the other hand, thrombosis is considered an overestimated means that many times results in serious complications, for example, immobilization of blood due to obstruction occurs within the blood vessel and ultimately causes death in many severe conditions.

The main reason behind the appearance of hemostasis is that it consists in the activation of the coagulation mechanism to prevent blood flow from a lesion in the vessel walls; On the other hand, the main reason why thrombosis occurs is that it includes a process known as Virchow’s triad that generally explains the factors that take place and contribute to the production of a clot in excessive behavior consisting of stasis, hypercoagulability. , as well as endothelial injury.

The different types of hemostasis are described to control bleeding using mechanical agents, chemical agents and physical agents depending on the situation. In contrast, the thrombus contains two types, such as arterial thrombus and venous thrombus.

The process of hemostasis is achieved when there is a rupture of the vessel that includes vascular constriction, formation of platelet plugs, formation of blood clots and growth or dissolution of fibrous tissue; while thrombosis occurs when there is injury to the blood vessel, impaired blood flow and abnormal blood clotting.

Comparative chart
Haemostasis Thrombosis
The naturally occurring process to stop or control bleeding within the blood vessel occurs due to injury, resulting in blood clotting is known as hemostasis. The process by which a blood clot forms within the blood vessel that repeatedly blocks the normal flow of blood through the circulatory system is known as thrombosis.
Considered as
Regarded as the natural clotting process within the body that occurs primarily to stop the excessive flow of blood from the wall of a ruptured blood vessel that takes place due to injury. Considered an overestimated medium that many times results in serious complications, for example, immobilization of blood due to obstruction occurs within the blood vessel and ultimately causes death in many severe conditions.
Causes
The main reason behind the occurrence is that it consists in the activation of the clotting mechanism to prevent blood flow from a lesion in the vessel walls. The main reason is that it includes a process known as Virchow’s triad that generally explains the factors that occur and contribute to the production of a clot in excessive behavior consisting of stasis, hypercoagulability, and in addition to endothelial injury.
Steps
Vascular constriction
Platelet plug formation
Formation of blood clots
Growth or dissolution of fibrous tissue
An injury to the blood vessel.
Altered blood flow
Abnormal blood clotting
Types
Different types are described for controlling bleeding by mechanical agents, chemical agents, and physical agents. Contains two types, such as arterial thrombus and venous thrombus

What is hemostasis?

The natural biological process that takes place to prevent the body from losing a large amount of blood as a result of vascular injury is known as hemostasis. The basic process of hemostasis generally focuses on the complicated sequences of steps that are contained in the other blood cells, such as tissue factor (TF), the particular blood proteins known as clotting factors, and the action of platelets.

Immediately after injury to blood vessels occurs after pain, activated biological hemostasis kicks in and begins to form a series of steps. In the first step, vasoconstriction occurs to reduce blood flow to the affected area. After that, the flowing platelets will rush to the affected area and join the endothelium wall and combine in groups.

Platelet activation will initiate the next series of enzymatic reactions, which will also result in clotting. Additionally, upon completion of these action steps, a protein is formed, called fibrin, producing an established hemostatic wadding, which then stops further bleeding.

What is thrombosis?

A process that involves the formation of a thrombus or a blood clot within the vessel is called thrombosis. The main mechanism of thrombosis is very similar to the process of hemostasis. Complications or intensity of thrombosis is relatively higher and occurs due to fundamental health conditions.

The clot formed from abnormal conditions blocks normal blood flow and ultimately leads to serious health conditions if the clot moves within the blood vessel, which supplies blood to vital organs of the body, for example to the brain and lungs.

There are two types of thrombosis; Venous thrombosis and arterial thrombosis. Venous thrombosis contains renal vein thrombosis, deep vein thrombosis, cerebral vein thrombosis and portal vein thrombosis, etc. Arterial thrombosis usually occurs due to an atheroma rupture in the arteries or due to stasis that was started by atrial fibrillation in the heart.

The pathophysiology of thrombosis or thrombus formation is explained by a triangle, which is Virchow’s triad. It provides factors including blood vessel injury, abnormal blood flow in the vessels, and hypercoagulability of the blood.

Key differences

  1. Haemostasis is known as the process that takes place within the blood vessel to stop or control bleeding resulting from injury and forms clotting (the blood goes from a liquid to a gel state). On the other hand, thrombosis is known as the state in which an abnormal blood clot forms within the blood vessel, consequently obstructing the normal flow of blood through the circulatory system, often resulting in many problems. like embolization.
  2. The reason for the formation of hemostasis is the stimulation of the coagulation flow in a lesion of the blood vessel wall. On the contrary, the reason for the appearance of thrombosis is a process known as Virchow’s triad, which gives some factors that are endothelial injury, stasis and hypercoagulability to explain abnormal and excessive clot formation.
  3. Haemostasis contains different types that are used when the body does not do it naturally, and these methods are some mechanical agents, physical agents, and chemical agents that are used depending on the situation. Another type of developmental hemostasis is used to refer to the differences in the homeostatic system between adults and children. While thrombosis contains two types given as arterial thrombus and venous thrombus.

Final Thought

The above discussion concludes that hemostasis is the natural blood clotting process resulting from injury to a blood vessel. At the same time, thrombosis is the abnormal formation of a blood clot within the blood vessel, obstructing the normal flow of blood.

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